167 Comments
User's avatar
Robert Yoho, MD's avatar

Thanks to all for your contributions. I am still chasing down leads.

Malone is old news, and it surprises me that anyone follows him. If you have the slightest interest in what I think about him, go to the upper right-hand corner in the search bar and enter his name. You will see a fair amount of my writing about Mr. Malone. He is a conspiracy apologist and denier.

Cindy's avatar

I take something called Blue Shrooms. It has 7 organic mushrooms and MB. I am completely off of my anti-depressant and have been for more than 6 months. I have been on anti-depressants since childhood and I will soon be 65. For me it's worked great.

John's avatar

Taken in proper amounts it’s fine!

Homeschool Freebie's avatar

Cindy, do you have a link to that? Tnx

Wise Old Woman in the Woods's avatar

That is amazing. Congratulations.

pimaCanyon's avatar

Cindy, how many of these do you take per day?

Cindy's avatar

I was taking 3 a day dropped back to 2 a day b/c was concerned about what they were saying but Dr. Yoho said he thinks the dose is ok when I asked the question about second guessing taking 3 a day.

Homeschool Freebie's avatar

Thanks for the amazing update. It really did seem strange to have that "emergency" warning suddenly flip the table. I'm wiping the dust off my bottle of MB even as I read this.

Atlandea's avatar

Dr Yoho, are you familiar with Chase Hughes and his miracle using MB?

https://www.youtube.com/watch?v=W4tXqcXeHHM&t=995s

Robert Yoho, MD's avatar

thanks will look!

iheartpugs's avatar

Great video - thanks for sharing!

Collapse Podcast's avatar

As well as melatonin

Martha's avatar

Honestly Dr Y., the best response to Parkinson's is classical homeopathy and Vitamin D IMHO.

But not the store brands Vitamin D/hormone. The best natural source and sadly the most expensive in the world, is a brand of cod liver oil. Highly absorbable vs the stuff we get in health food stores. Almost all other brands were tested and all were deemed rancid.

My mother suffered from Parkinson's and I placed her with a Movement Disorder clinic in Montreal. They did wonders titrating her levodopa meds and she was to be put on a "coffee" trial, but died in a freak accident soon after. Most people don't realize that neurologists only deal with Parkinson's and MS rarely; it's generally 2% of their practice so they are happy to refer patients to an MD clinic where the treatment is more focused. That's on the conventional side of medicine.

But on a more natural level, I tried to get my mother to call my Homeopath - one of the best in the world, considering the notable people who call him for his expertise. I don't want to put his name out here in public, but if you tell me you are interested, I can ask him if he would mind if you could contact him as he's not taking new patients.

As well, I don't want to endorse this brand of CLO in particular after what I said about most of them being rancid, and again if you are interested, I'll email you the brand.

But honestly, I've never seen any therapy work as well as homeopathy and I'm close to your age.

I'm not saying others therapies do not work, but after 45 years studying and reading and experimenting with all kinds of therapies, it's the only one that profoundly sticks.

Martha's avatar

I tried but it bounced back as undeliverable.

Andrew Devlin's avatar

This brings me back to a time in my youth when a screwball friend of mine slipped a few drops in his parent’s coffee to watch them freak out about their blue or green urine. Who knew that he was actually improving their health???

Fain Zimmerman's avatar

Yes, your urine can stain the the toilet bowl and is very difficult, re impossible to completely remove!

Paul D's avatar

Hi Robert, thanks for fantastic content. I was taking MB 10 years ago long before it entered the biohacking space. Imo liquid is untennible and impractical, get good capsules. I increased to 120mg/day for a viral condition and have been at that for 3 months, the difference over an 12mg/day I used for years is profound. I strongly suggest trying it is perfectly safe.

Truth Seeker's avatar

"viral condition" = symptoms allegedly caused by the elusive "virus"

The critter that has never been isolated, shown to cross infect, etc etc

Benefits may be for other reasons.

Might be useful to suggest how the 120mg per day amount was determined

In any case its still ~ half of known toxicity concerns

ThreeArchBay's avatar

Interesting, I may try it... but... "safe"? perhaps not so much when taking other drugs or supps, like I do...

Tramadol? Chlorpheniramine?

Dave Bross's avatar

I'm probably an outlier (frequent occurrence) but when I decided to try MB, a tiny test dose provoked a violent reaction along the lines of your phrase "neurological toxicity." Everyone is different so it pays to start small when trying something new.

Robert Yoho, MD's avatar

you are herxing

Jewell's avatar

Great post. I've been taking MB for years. I first used the drops but recently switched to Nutricel Blue Boost pills -12 mg. The warning against using with SSRIs is on every bottle. I found Mark Sloan's book on the ultimate guide to methylene blue very interesting and helpful. I've missed a few of your post so not sure if you ever looked into nicotine patches, gum or the like for PD.

Dana Thynes's avatar

Dr. Yoho, Thank you for this comprehensive, informative article. I, too, totally backed off of MB last year after reading Dr. Breggin's article, though I was only in the investigatory stages, and not actively taking it. I am eager to share this article!

Your link to the Gonzales-Lima study titled "Protection against neurodegeneration with low-dose methylene blue and near-infrared light" did not bring up the article for me. I found it at:

https://pmc.ncbi.nlm.nih.gov/articles/PMC4428125/

pimaCanyon's avatar

I read (quickly) this article. Certainly looks promising. One thing I couldn't find though was the dose he's talking about. He uses the term "lose dose" or "low level" but he doesn't define exactly what that is. I think anything from 4 or 5 mg up to 30 mg would be considered low dose.

Do you know what dose level he's referring to?

Dana Thynes's avatar

Yes, he said he is taking 5 mg a day, mixed with “any amount” of sodium ascorbate to prevent the blue staining of the mouth.

pimaCanyon's avatar

no, I meant the dosing in the Gonzales article. Does Gonzales mention the amount? 5mg is what Dr Yoho is taking.

Dana Thynes's avatar

I don't remember!

Vee's avatar

I had great respect for Dr. Breggin and Ginger Breggin until they censored me from their substack comments for being critical about Trump and calling out the Trump "assassination attempt" as a hoax. While they mean well, they are also human beings with biases, blinders, and plenty of cognitive dissonance.

The nail in the coffin for me is when Peter Breggin showed his true ignorance on the Doc Malik podcast with his blanketed support for the terrorist state of Israel. Such a shame for a brilliant man that I always thought was on the right side of history.

Craig's avatar

Thank you for this article. My wife and I (both 75 years old) had been taking it daily until I read some article that said it was bad. We were taking it prophylactically because it sounded generally heathful. After reading this article I guess we will go back to taking it daily. I also ran across silica water for Alzheimer's, Autism, Stroke, and I think I saw Parkinson's. I heard about it from Dennis N. Crouse's website and an interview he gave. https://prevent-alzheimers-autism-stroke.blogspot.com/ He says Fiji water has adequate amounts of silica but it is pricey. He has a recipe to make your own using sodium silicate and sodium bisulfate. I ordered the ingredients and am going to give a try.

Collapse Podcast's avatar

Biosil drops - contain both silica and choline & you can find them fairly easily

Ionome Labs's avatar

the dose concentration so too low to be useful. waste of money for Al detox.

Collapse Podcast's avatar

Thank you. In terms of Al you are right. For some reason, I thought they had more per serving vs Fiji. It is effective at that level for other uses, as well as the added benefit of choline.

ThreeArchBay's avatar

I had read that diatomaceous earth is loaded with silica... perhaps worth looking into?

I used to take it... 1tsp/day... did not see any pos benefits (no bad effects at all)... so I stopped...

Ionome Labs's avatar

doesn't absorb so won't do anything for Al tox.

Steve  Mitzner's avatar

Considering our 62 million in fraud fines & leader in cause of iatrogenic death/ [the kills 250K to 700+K] each year/ [600 to 900 a day] Big Pharma "medicine" how could one trust anything they say? And that's not considering all the Coved murders documented in the book,

What the Nurses Saw! God help us & save us from Big Pharma's "medicine"!!!

pimaCanyon's avatar

I think the fines are actually bigger than that.

Merck alone has paid over $5.8 BILLION to settle lawsuits related to Vioxx, which includes compensation for those injured or who suffered a heart attack or stroke after taking the drug. This amount also covers fines and penalties associated with its marketing practices.

Bill Bradford's avatar

I read Dr. Breggin's "Toxic Psychiatry" well over 30 years ago. It literally saved my life. So my question to you, Robert, is this: In simplest, most basic terms, what is the root cause of your Parkinson's? Genetic? Environmental? What, exactly, CAUSED it?....

Robert Yoho, MD's avatar

mercury amalgams, 17 of them. Read Judas Dentistry

KT-SunWillShineAgain's avatar

If you have had 17 mercury amalgamation and still have them, you would test high for mercury, and that mercury poisoning can trigger all kinds of problems, including PD.

Hopefully you have had them carefully carefully removed and replaced with composite?

If you haven't, then you would need to seek out a biologically oriented dentist that practices systemic dentistry.

The challenge is how to carefully chelate the mercury?

Robert Yoho, MD's avatar

read Judas Dentistry and my OSR posts

Wise Old Woman in the Woods's avatar

he did. I think he went to a dentist in Mexico. His wife needed more extensive work so they went to Spain for a specialist.

Fain Zimmerman's avatar

Many years ago I had all 12 of mine removed. My only regret is that it should have been slower to give the body time to deal with the mercury fumes more slowly.

Bill Bradford's avatar

THANK-YOU! KEEP UP the GOOD WORK!.... I'd forgotten about those mercury amalgams!....

KT-SunWillShineAgain's avatar

Dr. Sabine Hazan has had good outcomes with treating the gut microbiome for PD.

Men in their 40s having early onset of PD are found to have contributed to early onset with nutrient poor diet of processed foods (fast food) along with soft drinks and high aluminum and mercury levels.

By restoring microbiome, the PD slowed down and patients began to recover.

Its all about the Bifidobacteria.

Also check out Unbekoming posts on detoxing from high mercury and aluminum.

Make sure your lithium levels aren't low, it's one of the 12 essential minerals and Is being used to treat Alzheimer’s.

Robert Yoho, MD's avatar

all good but infections are upstream and should be treated first IMHO

KT-SunWillShineAgain's avatar

Hazans early PD onset didn't have any infection. She was approached to see if there was someway to treat early onset PD via the gut microbiome and there is. Hazan has substack/blog, check it out , she's doing fantastic research.

Collapse Podcast's avatar

Interesting you brought up Dr. Hazan, reading her work was the first time I learned MB wipes out bifido, which was the only drawback I saw.

,

KT-SunWillShineAgain's avatar

https://m.youtube.com/watch?v=cuksoOOwr7c

https://x.com/newstart_2024/status/2024961245623820760

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Conversation

Camus

@newstart_2024

Dr. Sabine Hazan drops a chilling truth: Parkinson's and Alzheimer's symptoms often start in your gut—up to 20 years BEFORE brain issues show up.

In this clip, she explains:

- Constipation can be an early Parkinson's red flag (20+ years prior).

- Gut dysbiosis is a massive early hint.

- Long COVID, chronic fatigue, Lyme—many trace back decades: appendicitis (loss of microbiome reservoir), antibiotics, infections… a domino effect that quietly builds until the body collapses.

- “It doesn’t start overnight. It’s been accumulating… one domino falls, hits the next, until the whole set is down.”

The microbiome isn’t just “gut health”—it’s potentially the earliest warning system for neurodegenerative disease.

If gut issues are the first domino… what’s one early gut symptom you’ve noticed in yourself or someone close that you now wonder about?

Robert Yoho, MD's avatar

all nice but if you have huge active Lyme w 4 species that takes priority

KP Stoller's avatar

I think if there is an issue with MB it is quality because not all MBs are created equal and as with any intervention there is always someone somewhere that will have an untoward reaction to almost anything but we don't really know who those folks are. I would still use 4PAS for those with tremors just in case we are dealing with manganese toxicity. And hyperbaric oxygen is a nice complement.

Robert Yoho, MD's avatar

this guy is a curmudgenonly genius

Marlene Mc's avatar

I so hope this helps you Dr. Yoho. You will find a way!